![]() Conclusion: Recovery of adrenal insufficiency, due to causes other than autoimmune adrenalitis, has been reported in the past. A repeated ACTH-stimulation test revealed a basal cortisol of 0.25 µmol/l and a peak cortisol of 0.30 µmol/l with a basal ACTH of 178 pmol/l. Eventually, the patient decided to stop his medication completely. ![]() ![]() During the following years the dose of hydrocortisone was gradually decreased. The diagnosis of autoimmune Addison’s disease was made and replacement therapy with hydrocortisone and fludrocortisone was started. A CT-scan showed no evidence of calcifications or other abnormalities of the adrenal glands. Adrenal auto-antibodies were weakly positive. Cortisol failed to increase during the ACTH stimulation test (0.02 to 0.03 µmol/l) and ACTH was markedly elevated (920 pmol/l). Laboratory tests showed a plasma cortisol of 0.02 µmol/l (08:30 h). During physical examination hyperpigmentation was seen. ![]() Case: A 39-yr-old male was referred because of extreme fatigue, weight loss, anorexia, nausea, and bouts of fever. We describe a patient with primary adrenal insufficiency caused by autoimmune adrenalitis in whom partial remission was observed after 7 yr. ![]() Objective: To our knowledge, no case of remission in autoimmune Addison’s disease has previously been reported. ![]()
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